Detroit Lions vs. San Francisco 49ers Same Game Parlay Picks, Odds & Predictions

Detroit Lions vs. San Francisco 49ers Same Game Parlay Picks, Odds & Predictions Recap

The Detroit Lions secured a thrilling 40-34 victory over the San Francisco 49ers allowing us to cash both legs of the MNF same-game parlay in at Caesars Sportsbook. Showcasing their offensive prowess and resilience in a game that unfortunately carried little playoff implication but significant emotional weight, Dan Campbell’s troops avenged last year’s playoff loss to the reigning NFC champs. Jared Goff led the Lions with 253 passing yards, completing 22 of 28 passes and throwing three touchdowns, including a pivotal 4-yard strike to Amon-Ra St. Brown in the third quarter to take the first lead of the match. The Lions’ run game was also dominant, with Jahmyr Gibbs rushing for 117 yards and a game-sealing 30-yard touchdown late in the fourth quarter. By combining for 439 yards of total offense and 6.4 yards per play, the Lions outlasted the Niners to secure their 14^th win of the NFL betting season helping to easily cash over tickets.

Key plays put us in line to cover the NFL odds with Kerby Joseph intercepting Brock Purdy twice in the second half, flipping momentum in Detroit’s favor. Joseph’s first interception set up the Lions’ go-ahead score, while the second paved the way for Gibbs’ decisive run. Detroit’s offense was nearly flawless early, scoring on its first five possessions, including a creative hook-and-ladder touchdown featuring Amon-Ra St. Brown and Jameson Williams with the former finishing with 10 catches for 94 yards and the latter tallying a pair of first half touchdowns.

San Francisco couldn’t keep pace despite Purdy’s strong start, completing his first 11 passes. He totaled 271 yards, one touchdown, and two interceptions before leaving the game with another elbow injury. Had the injury bug not targeted the Niners QB1, it’s certainly within the realm of possibility that Detroit loses this game. Immediately upon his departure, the Lions’ defense stiffened limiting San Francisco to just six fourth quarter points. With this victory, Detroit remained unblemished away from Ford Field for the entirety of the regular season. The Lions will now prepare for a Week 18 showdown against Minnesota, with the NFC North title and top seed in the playoffs on the line.

Detroit Lions vs. San Francisco 49ers Same Game Parlay Picks, Odds & Predictions

Week 17 NFL betting action closes out in Silicon Valley where the San Francisco 49ers will attempt to play the role of spoiler by ousting a Detroit Lions squad fighting to the death with the Philadelphia Eagles and Minnesota Vikings for the No. 1 seed in the NFC playoffs. Dan Campbell’s troops took a step closer last week in Chicago where it handled the Bears with ease en route to logging the 34-17 win and cover to remain perfect away from Ford Field. Already knowing it was eliminated from postseason play before the game against Miami kicked off, Kyle Shanahan’s squad fought valiantly through three quarters and was in position to end the Fins season before a crucial late-game turnover nixed that opportunity.

Caesars Sportsbook initially set the Lions as 2.5-point favorites on the NFL odds with a total of 51.5 for this now less intriguing NFC clash. NFL bettors have since pushed the number to beat out to -3.5 with 70+ percent of the bets and money aligned with Detroit minus the road chalk. Though 80 percent of the booked handle on the total is currently riding the over, reverse line movement has pushed the impost down a point to 50.5 letting it be known that more respected sharp money expects points to be tougher to come by than expected.

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Detroit Lions vs. San Francisco 49ers NFL Same Game Parlay:

The Detroit Lions bounced back from a tough loss to the Bills that halted the win streak with a commanding 34-17 victory over the struggling Chicago Bears, notching their 13th win of the season and covering the NFL spread. Unlike their Thanksgiving Day collapse against Chicago, the Lions maintained control from start to finish, taking a dominant 27-7 lead into halftime and closing out strong. Jared Goff excelled in the cold, posting an impressive 137.0 QB rating with 336 passing yards and three touchdowns. Jahmyr Gibbs shone in an expanded role, amassing 154 scrimmage yards and a touchdown. Amon-Ra St. Brown and Jameson Williams each hauled in receiving touchdowns, but the game’s standout moment came on a brilliantly designed fake busted play that ended in a touchdown pass to tight end Sam LaPorta. Offensive coordinator Ben Johnson once again showcased his creative play-calling, further solidifying his reputation as a top coaching prospect. Despite the offensive fireworks, Detroit’s injury-depleted defense remains a concern, and its vulnerabilities could be exposed in high-pressure situations. As the Lions prepare for a high-stakes Week 17 showdown against the NFC champion San Francisco 49ers on Monday Night Football, the onus will be on their potent offense to rise to the occasion and deliver another electrifying performance.

The San Francisco 49ers entered Week 16 with the knowledge that their playoff hopes had officially been extinguished prior to kick-off against the Miami Dolphins. Their ensuing 29-17 loss, coupled with a failure to cover the closing NFL odds, epitomized a disappointing season for the defending NFC champions. The defeat marked their ninth of the year and confirmed their absence from the postseason for the first time in three years. Persistent issues—penalties, turnovers, and inefficiencies on third downs and in the red zone—once again undermined their efforts. Injuries, a recurring problem throughout the season, have left the roster in constant flux, raising questions about who will be available for their Week 17 Monday Night Football clash against the Detroit Lions. With a potential draft position at No. 11, motivation becomes a significant concern for a team now playing for little more than pride. Early betting indicators show minimal enthusiasm for backing the home side, with expectations of a low-scoring game despite the elevated total. Whether the 49ers can reclaim some dignity in their remaining contests remains uncertain, as their focus may already be shifting to rebuilding for next season.

The Niners undoubtedly have the offensive personnel to hang with any team in the league. When not under duress, Brock Purdy can sling the pigskin around with the best of them. Deebo Samuel showed he still has some juice after balling out with his best showing of the year against the Dolphins. George Kittle has arguably been one of the best tight ends in the NFL. This trio will most definitely relish the opportunity of running up against an injury-ravaged Lions defense that’s served up an average of 29 points per game over the last month. However, San Fran’s offensive line is in shambles with Trent Williams one of many hogs already listed as out, doubtful, or questionable. With that, I can see why the betting public is siding with the Lions as road favorites. In the grand scheme of things, I don’t believe the NFL spread comes into play in this one. Detroit either wins going away or loses outright. A last second field goal isn’t deciding this one. With that, I’ll side with the soon to be named top seed in the NFC and look for the teams to put on a show to close out Week 17.

• DETROIT LIONS -3.5
• DETROIT/SAN FRANCISCO OVER 50.5

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